Abstract Mental health is a vital component of adolescent well-being, influencing academic performance, social functioning, and quality of life. This study aimed to assess the knowledge, attitude, and practices related to mental health among higher secondary students. A descriptive cross-sectional design was adopted, and 300 students were selected using stratified disproportionate random sampling. Data were collected through validated structured questionnaires. The findings revealed that 61.0% of students had average knowledge, 31.3% had good knowledge, and 7.7% had poor knowledge regarding mental health. A favorable attitude was observed among 98.3% of participants. Common practices to maintain mental wellbeing included physical activity, listening to music, and seeking support from trusted individuals. Awareness is required to enhance the mental well being of the adolescent. Methods A descriptive cross-sectional study was conducted among 300 higher secondary students selected using stratified disproportionate random sampling. Data were collected using validated structured questionnaires to assess knowledge, attitude, and practices related to mental health. Results The study revealed that 61.0% of students had average knowledge, 31.3% had good knowledge, and 7.7% had poor knowledge regarding mental health. A favorable attitude towards mental health was observed in 98.3% of participants. Common practices for emotional management included physical activity or listening to music (52.3%) and talking to a trusted person (29.0%). Nearly half of the students preferred seeking help from parents or guardians for substance abuse–related issues.