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Article . 2026
License: CC BY
Data sources: Datacite
ZENODO
Article . 2026
License: CC BY
Data sources: Datacite
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Rabies Vaccine Failure Revisited: Integrity, Manufacturing Technologies, and Public Health Implications

Authors: Sushil Kumar*, Newton Biswas, Kiran Singh, Shivangi Bhardwaj;

Rabies Vaccine Failure Revisited: Integrity, Manufacturing Technologies, and Public Health Implications

Abstract

Rabies is a universally fatal zoonotic disease once clinical signs appear, yet it is entirely preventable through timely vaccination and post-exposure prophylaxis. Modern cell-culture rabies vaccines have demonstrated high efficacy and safety over several decades. Recent international alerts regarding the circulation of falsified rabies vaccine batches have generated concern and have been widely reported as “rabies vaccine failure.” This article critically examines the concept of rabies vaccine failure, differentiating true biological failure from pharmaceutical quality and supply-chain failures. In addition, current rabies vaccine production technologies, manufacturing processes, and quality control measures are reviewed. The implications of counterfeit vaccines for clinical practice, public trust, and regulatory systems are discussed. Evidence indicates that recent events reflect failures of product integrity rather than intrinsic limitations of rabies vaccine technology. 

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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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