Abstract Introduction: High-resolution computed tomography (HRCT) imaging clearly and rapidly reveals pulmonary pathologies invisible to the naked eye. Chronic Obstructive Pulmonary Disease (COPD) is a prevalent, preventable, and treatable disease characterized by persistent respiratory symptoms and airflow limitation due to airway and/or alveolar abnormalities. Aims and Objectives · To find out the severity of disease in COPD by correlating spirometric values with different patterns on HRCT. Objective · Primary: To determine different HRCT patterns and its co-relation with spirometric values in patients with COPD. · Secondary: To determine the association of severity of disease in COPD patients with different HRCT patterns. Material and Method Study Design: Descriptive and Observational Study Study Period: 18 months Study Place: Department of Respiratory Medicine at Hind Institute of Medical Sciences, Barabanki. Sample Size: Total Sample were 70. Study participants: Patients with age group >35 years attending the OPD and IPD in the Department of Respiratory Medicine. Sampling Method: Consecutive Sampling Technique Result: In this study, male (64.29%), had a mean age of 58.25 years (SD ±9.53), with the highest prevalence (32.86%) in the 56–65 years age group, followed by 25.71% in the 46–55 years group. Discussion: Patients in the study exhibited relatively uniform distributions of HRCT and spirometry patterns, enabling a clear examination of trends according to age, gender, and the interplay of both factors.