We present a new global analysis of nuclear PDFs in the nCTEQ approach. Building on a modern proton baseline without nuclear data, we combine and update previous separate analyses that focused on JLab neutral-current DIS, neutrino DIS and dimuon production, and the currently available LHC data, in particular on W/Z and heavy quark production. For the latter, we not only employ a data-driven approach, but also perform an alternative fit based on NLO QCD and the ACOT variable flavor number scheme. As a result, we obtain PDFs with reduced uncertainties in both the high-x and low-x regimes, in particular for the gluon and the strange quark. We also present predictions for observables that were not included in this analysis.