Background: Closure of the subcutaneous tissue plane plays an important role in wound healing, and different techniques have been proposed to reduce complications such as seroma, infection, and wound dehiscence. Materials and Methods: This was a hospital based cross sectional analytical study conducted among Patients undergoing abdominal surgeries at Bharati Vidyapeeth (Deemed to be University) Medical College and Hospital, Sangli, over a period of 18 months. Results: In Comparison based on the Surgery, where the incidence was high among the emergency surgeries in which suture closure of subcutaneous tissue is done. In Comparison according to Nature of the wound, all patients among suture closure of dirty wounds developed complication. In Comparison of wounds Complication among the two groups, the lower incidence of seroma in the drain group was not statistically significant. In Comparison based on Wound length in cm, Complication rate is around 42% among suture length of 4-7cm and it is 33% among suture length 8-11cm. In Comparison of period required for complete wound healing with removal of all sutures, among drain group complete suture removal done within 15 days among around 95% patients. Conclusion: The study conducted at tertiary care center to observe the results of subcutaneous suture closure group versus NSD conclude incidence of seroma formation, SSI, superficial wound dehiscence was found to be lower among drain group but the difference was not statistically significant. Wound healing is better among the NSD group. Considering the observations, use of NSD for subcutaneous tissue closure in contaminated, dirty wounds, and in patients with comorbid conditions, reduces postoperative complications and achieves better wound healing