This manual summarizes the approach to consultative research ethics review described in the Document “Consultative Research Ethics Review: Concept Note/Manual”. The Consultative Ethics Review is dialogic and supportive in character, its implementation requires face-to-face meetings between researchers and research ethics peer reviewers. The consultative nature of the methodology means that the process results in recommendations and suggestions of improvement in a study from the perspective of research ethics (for example, measures to improve participants’ safety). During the meeting most questions that the researchers may not have been able to address sufficiently in writing in their form for requesting review, can be immediately clarified. A typical question that is often left unanswered in application forms – as misinterpreted to be relevant only to clinical research – is the inquiry concerning potential unintended or unexpected findings in social science research. Face-to-face meetings facilitate the dialogue between researchers and ethics committee members. The attitude adopted by the committee members is that of a “critical friend”; the members’ task is to point out the potential concerns in the proposed work while guiding the researcher to improving the research design from the perspective of research ethics.