To search for bifunctional luminescent platform for optical manometry and thermometry, the Cs2TeCl6 nanocrystals were prepared. Excited at 456 nm, the designed nanocrystals emitted dazzling orange emission centered at 596 nm, arising from self-trapped exciton emission, whose fluorescence intensity, full width at half maximum (FWHM) and decay time were sensitive to temperature. Through analyzing the temperature-dependent lifetime, the thermometric properties of the resulting nanocrystals was evaluated, resulting in high relative sensitivity of 3.76% K-1. Moreover, the in-situ pressure-dependent Raman and emission spectra were tested to clarify the potential of the developed nanocrystals for optical manometry. The pressure-related Raman spectra demonstrated the splendid structural stability and reversibility of the studied sample. Via studying the pressure-dependent Raman modes, one knows that the maximum pressure sensitivity of Cs2TeCl6 nanocrystals was 9.62 cm-1/GPa. Furthermore, when pressure was increased, distinct spectral blue-shift was observed in the synthesized nanocrystals, contributing to the controllable luminescence at high-pressure, i.e., the emitting color changed from orange to yellow. Through analyzing the pressure-dependent emission band centroid and FWHM, one knows that the maximum pressure sensitivities of the resultant nanocrystals were 3.54 and 4.82 nm/GPa, respectively. Notably, when the color coordinate was adopted as the manometric parameter, colorific pressure sensing was also realized in the designed nanocrystals, resulting in a relative sensitivity of 4.62% GPa-1. Our findings imply that the utilization of high-pressure and low-temperature stimuli is an efficient route to regulate the luminescence properties of the Cs2TeCl6 nanocrytals, ensuring their feasibilities in optical thermometry and manometry.