Abstract A universal physical theory is presented, based on the concept of the flytron — a fundamental triune structure that unifies the topological, geometric, and informational aspects of physical reality. A flytron is defined as a triple F = (M, ∂M, I^), where M is a compact manifold, ∂M is its boundary structure, and I^ is a self‑adjoint operator specifying the informational component. On the basis of this structure, a universal Lagrangian is formulated, incorporating topological, geometric, operator, and gauge blocks. It is shown that the Maxwell, Einstein, and Schrödinger equations arise as strict special cases of the flytronic evolution equation. A consistent dynamics of three levels — topology, metric, and informational operator — is developed. Equations are obtained that describe the evolution of the manifold boundary, the change of space‑time geometry, and the quantum development of states. Symmetries and conservation laws are investigated, including Noether currents and the flytronic energy‑momentum tensor. Experimental predictions are presented, covering quantum spectra, electromagnetic signals, gravitational waves, cosmological observations, and high‑precision laboratory effects. The limitations of the model and its behavior in sub‑Planckian and strong‑field regimes are discussed. Flytronic dynamics demonstrates the possibility of unifying quantum mechanics, gravity, and topology within a single mathematical construction and forms the basis for further development of ontologically oriented physics.