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Article . 2026
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2026
License: CC BY
Data sources: Datacite
ZENODO
Article . 2026
License: CC BY
Data sources: Datacite
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DESEMPENHO CLÍNICO DA MEMBRANA DE COLÁGENO E DO HEMOSPON EM ALVÉOLOS PÓS-EXTRAÇÃO: UMA REVISÃO DE LITERATURA

Clinical performance of collagen membrane and Hemospon in post-extraction alveolar sockets: a literature review
Authors: Azenha dos Santos, Joelisa; Ribeiro Costa, Giovana Caroline; Pereira Verona, Júlia Roberta; Santana, Yasmin Stefani; Faco, Eduardo; De Lima Sousa, Leandro Lécio; Charifker ribeiro martins, Sergio; +1 Authors

DESEMPENHO CLÍNICO DA MEMBRANA DE COLÁGENO E DO HEMOSPON EM ALVÉOLOS PÓS-EXTRAÇÃO: UMA REVISÃO DE LITERATURA

Abstract

A cicatrização alveolar após a extração dentária representa um processo biológico complexo e decisivo para o sucesso dos procedimentos restauradores subsequentes. A literatura evidencia que a perda precoce do rebordo alveolar, associada à resposta inflamatória local, pode comprometer a estabilidade tecidual e aumentar o desconforto pós-operatório. Nesse contexto, o uso de biomateriais tem sido investigado como uma estratégia para estabilizar o coágulo, controlar o sangramento e favorecer um reparo previsível. Objetivo: A presente revisão de literatura analisou estudos que avaliavam o desempenho clínico da membrana de colágeno e do Hemospon em alvéolos pós-extração, com foco na hemostasia, dor e cicatrização inicial. Metodologia: A busca foi realizada na base PubMed e, após critérios rigorosos, 12 estudos publicados entre 2024 e 2025 foram incluídos. Resultados: As evidências convergentes disponíveis na literatura demonstravam que a membrana de colágeno apresentava ampla aplicabilidade clínica, atuando como barreira biológica capaz de proteger o coágulo, modular a resposta inflamatória e favorecer a organização tecidual, sendo frequentemente associada à preservação alveolar e à regeneração óssea. Os estudos também indicavam melhor manutenção do volume alveolar e do reparo, especialmente em associação a biomateriais enxertáveis. Por outro lado, o Hemospon, de gelatina suína liofilizada, promovia hemostasia imediata e cicatrização dos tecidos moles, sem relação direta com a regeneração óssea avançada. A análise conjunta dos dados indicava que esses biomateriais apresentam funções clínicas complementares. Conclusão: Os achados evidenciam que o Hemospon e as membranas de colágeno apresentam desempenhos clínicos distintos e complementares, devendo a seleção do biomaterial considerar os objetivos do procedimento cirúrgico e as necessidades específicas de cada paciente, à luz das evidências científicas contemporâneas.

Alveolar healing after tooth extraction represents a complex biological process that is decisive for the success of subsequent restorative procedures. The literature demonstrates that early loss of the alveolar ridge, associated with the local inflammatory response, may compromise tissue stability and increase postoperative discomfort. In this context, the use of biomaterials has been investigated as a strategy to stabilize the clot, control bleeding, and promote predictable repair. Objective: The present literature review analyzed studies that evaluated the clinical performance of collagen membrane and Hemospon in post-extraction sockets, focusing on hemostasis, pain, and initial healing. Methods: The search was conducted in the PubMed database and, after rigorous criteria, 12 studies published between 2024 and 2025 were included. Results: The convergent evidence available in the literature demonstrated that collagen membrane presented broad clinical applicability, acting as a biological barrier capable of protecting the clot, modulating the inflammatory response, and promoting tissue organization, being frequently associated with alveolar preservation and bone regeneration. The studies also indicated better maintenance of alveolar volume and repair, especially when associated with grafting biomaterials. On the other hand, Hemospon, composed of lyophilized porcine gelatin, promoted immediate hemostasis and soft tissue healing, with no direct relationship to advanced bone regeneration. The joint analysis of the data indicated that these biomaterials present complementary clinical functions. Conclusion: The findings demonstrate that Hemospon and collagen membranes present distinct and complementary clinical performances, and the selection of the biomaterial should consider the objectives of the surgical procedure and the specific needs of each patient, in light of contemporary scientific evidence.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average