In the Western world, Cannabis has been used as both medicinal and recreational substances. Around the world, cannabis grows wild in temperate regions such as central or western Asia, and possibly even eastern Asia. Moreover, it is cultivated in many countries. It is a treasure trove of phytochemicals and serves as a rich source of both cellulosic and woody fibers. Cannabis contains more than 100 different chemicals called cannabinoids. Cannabis in purified and standardized form have been made available for the manufacturing of several pharmaceutical drugs. Recreational use of this substance has been related to major acute cardiovascular disorders, such as stroke, myocardial infarction, arrhythmia, congestive heart failure, and epilepsy. Adults who are managing chronic pain can greatly benefit from cannabis. It reduces the symptoms of spasticity in fibromyalgia, multiple sclerosis, and obstructive sleep apnea syndrome. Additionally, it treats nausea and vomiting brought on by chemotherapy by acting as an anti-emetic. 38 US states, 4 US territories, and the US District of Columbia have made it lawful to consume cannabis for medical purposes. This review analyzes the medicinal use of cannabis, mentioning its history, active constituents, pharmacological actions, potential benefits, and risks.