This article presents a conceptual framework that explores the theoretical viability of employing functional adult human cortical tissue as an exogenous modulating node in emotional neural circuits. Grounded in well-established principles of synaptic plasticity, network-level modulation, and receptor-system-dependent neural integration, the proposed model does not presuppose the transfer of cognition, memory, or identity, nor does it imply immediate clinical applicability. Instead, the framework conceptualizes the grafted cortical tissue as a biologically active substrate, capable of indirectly influencing dysfunctional emotional dynamics through adaptive interactions with the recipient neural system. By distinguishing this approach from stem cell-based strategies and brain organoid models, the article seeks to clarify its theoretical boundaries and neurobiological plausibility. The proposed hypothesis aims to stimulate interdisciplinary discussions in theoretical neuroscience and neuroengineering, while outlining core conceptual limitations and potential directions for future investigations.