
Formal pre-registration of the hypothesis that pigmented biological structures across different tissues (iris nevi and cutaneous nevi) share measurable fractal and geometric organization principles. Defines two candidate metrics:- Δ_D: cross-tissue fractal correlation index (box-counting dimension)- Δ_A: cross-tissue golden proximity index (Auric Index extension) Predicts corr(D_iris, D_skin) > 0 and corr(A_iris, A_skin) > 0 across cohort n ≥ 40, p < 0.05. No code. Theoretical formulation only. Pre-registered to establish priority and date of formulation. Related records:- Iris pipeline v5.1: https://doi.org/10.5281/zenodo.18806604- Iris preprint: https://doi.org/10.5281/zenodo.18818856- Phyllotaxis base: https://doi.org/10.5281/zenodo.18760369
fractal dimension, iris nevi, cutaneous nevi, melanocyte organization, golden angle, Auric Index, cross-tissue correlation, uveal melanoma, melanoma detection, phyllotaxis, pigment
fractal dimension, iris nevi, cutaneous nevi, melanocyte organization, golden angle, Auric Index, cross-tissue correlation, uveal melanoma, melanoma detection, phyllotaxis, pigment
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