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Other literature type . 2026
License: CC BY
Data sources: Datacite
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ЁВВОЙИ НОК (PYRUS PYRASTER) МЕВАСИ ҚУРУҚ ЭКСТРАКТИНИНГ ГИПОГЛИКЕМИК ФАОЛЛИГИ

ЁВВОЙИ НОК (PYRUS PYRASTER) МЕВАСИ ҚУРУҚ ЭКСТРАКТИНИНГ ГИПОГЛИКЕМИК ФАОЛЛИГИ

Abstract

Ушбу фармако-токсикологик тадқиқотларда ёввойи нок меваси қуруқ экстрактининг ўткир заҳарлилиги аниқланди ҳамда унинг гипогликемик фаоллиги аллоксан билан чақирилган диабет шароитида ўрганилди. Дастлаб қуруқ экстрактдан 20 % ли суспензия тайёрланиб, у оқ сичқонларга оғиз орқали 1000 мг/кг дан 5000 мг/кг гача бўлган дозаларда юборилди. Оқ сичқонларда 14 кун давомида физиологик ва токсикологик ўзгаришлар кузатиб борилди. Кейинги тажрибаларда ёввойи нок (Pyrus pyraster L.) меваси қуруқ экстрактининг специфик гипогликемик фармакологик фаоллиги аллоксан билан чақирилган диабет моделида баҳоланди. Тажрибалар оқ каламушларда олиб борилиб, аллоксан моддаси қорин бўшлиғига 150 мг/кг дозада юборилди. Оқ каламушлар беш гуруҳга бўлиниб, ўрганилаётган қуруқ экстракт гуруҳларга мос равишда 150 мг/кг, 200 мг/кг ва 500 мг/кг дозаларда қўлланилди. Референс препарат сифатида БФҚ Фитодиабетол (МЧЖ “Акташ Фарм”) 100 мг/кг, дозада олинди

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    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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