Amlodipine, a dihydropyridine calcium channel blocker, is primarily prescribed for managing essential hypertension and angina pectoris. An overdose of calcium channel blockers can lead to severe hypotension and shock. We report a case of a 45-year-old male who was brought to the emergency department with altered mental status and shock after ingesting 200 mg of amlodipine. The patient’s circulatory shock was managed with inotropes and high-dose insulin therapy can restore myocardial metabolism and save lives.