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ZENODO
Dataset . 2026
License: CC BY
Data sources: Datacite
ZENODO
Dataset . 2026
License: CC BY
Data sources: Datacite
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TRIGEMINAL NEURALGIA: PATHOPHYSIOLOGY, DIAGNOSIS AND MODERN MANAGEMENT APPROACHES

Authors: Karomov Suhrob Mirmukhsin ugli;

TRIGEMINAL NEURALGIA: PATHOPHYSIOLOGY, DIAGNOSIS AND MODERN MANAGEMENT APPROACHES

Abstract

Trigeminal neuralgia (TN) is a chronic facial pain syndrome characterized by brief, recurrent episodes of intense, unilateral, shock-like pain within the sensory distribution of the trigeminal nerve. Despite its relatively low prevalence, the disorder causes marked functional disability and deterioration in quality of life. The underlying mechanism in classical TN is most commonly neurovascular compression that induces focal demyelination and abnormal excitability of trigeminal fibers. Secondary forms may develop in association with demyelinating diseases, tumors, or structural intracranial pathology. Diagnosis relies primarily on clinical evaluation, supported by neuroimaging to exclude secondary etiologies. Pharmacological therapy with sodium channel–modulating anticonvulsants remains first-line treatment, while surgical interventions are reserved for refractory cases. This article presents a synthesized overview of current concepts regarding the mechanisms, diagnosis, and management of trigeminal neuralgia.

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average