Community health worker (CHW) programmes have been implemented to improve tuberculosis (TB) treatment adherence in Ghanaian districts. A systematic literature review was conducted using databases such as PubMed, Scopus, and Google Scholar. Studies published between January 1, , and December 31, , were included based on predefined inclusion criteria. Data from the studies were analysed to identify patterns and trends in CHW programmes' impact on adherence. CHWs played a significant role in improving TB treatment adherence rates by up to 45% in selected districts compared to standard care groups. The most effective interventions included regular follow-ups, community education campaigns, and home-based support services. The review supports the efficacy of CHW programmes for enhancing tuberculosis treatment adherence in Ghanaian settings, although further research is needed to identify optimal programme configurations. Ghana should consider expanding its CHW programmes with a focus on community education and regular follow-ups to ensure sustained improvements in TB treatment outcomes. Treatment effect was estimated with $\text{logit}(p_i)=\beta_0+\beta^\top X_i$, and uncertainty reported using confidence-interval based inference.