Spinal-Multiple-Myeloma-SEG – GitHub Repository This Zenodo record archives the GitHub repository for the study "Spinal-Multiple-Myeloma-SEG", submitted to Scientific Data. The repository provides code for segmentation of the spine, vertebrae, and osteolytic spinal multiple myeloma lesions using the nnU-Net framework. The repository allows researchers to explore and visualize the spinal and lesion images from the dataset, supporting reproducibility and further development of segmentation pipelines. The GitHub repository is available at: https://github.com/MISAG-BUT/Spinal-Multiple-Myeloma-SEG. The dataset used for this work is publicly available via The Cancer Imaging Archive (TCIA): https://doi.org/10.7937/k4qv-hh78. Pre-trained nnU-Net models for spine and lesion segmentation are available in a separate Zenodo record: Spinal-Multiple-Myeloma-SEG nnU-Net Models. For detailed instructions on installation, dataset exploration, and running the segmentation pipeline, please see the README in the GitHub repository.