Infectious Bronchitis (IB) is one of the most widespread and economically damaging viral diseases of poultry across the globe. Once considered only a respiratory disease, it is now well recognized that the Infectious Bronchitis Virus (IBV) can simultaneously affect the respiratory system, kidneys, and reproductive organs. This multi-organ involvement makes IB a complex disease, capable of causing production losses in broilers, layers, and breeder flocks alike.