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ZENODO
Dataset . 2026
License: CC BY
Data sources: Datacite
ZENODO
Dataset . 2026
License: CC BY
Data sources: Datacite
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Integrated Human Early Embryo Atlas with Temporal Annotations

Authors: Gao, Handi;

Integrated Human Early Embryo Atlas with Temporal Annotations

Abstract

This repository provides the Human Early Embryogenesis Atlas used in the Gene-Chronos study, “Gene-Chronos: developmental time inference from single-cell transcriptomes using a pre-trained Geneformer adapter”. The atlas is a harmonized resource compiled from 12 publicly available human embryo single-cell and spatial transcriptomic datasets spanning early human development from Day 0 to Day 29 (E0–E29), comprising approximately 380,000 cells. This dataset was constructed to support biological time inference, temporal reconstruction, and cross-dataset transfer evaluation in early human embryogenesis. In the accompanying manuscript, it is used as a large-scale atlas resource for evaluating developmental time prediction and transfer generalization. The processed data are provided in unified .h5ad format for downstream computational analysis. Files included:- Integrated_Human_Embryo_Atlas.tar.gz: compressed archive containing the processed .h5ad files. Detailed dataset sources, accession numbers, developmental stages, and composition summaries are provided in the accompanying manuscript and supplementary materials. This dataset was generated to support the Gene-Chronos study. Users of this resource are encouraged to cite the associated Gene-Chronos publication when it becomes available.

AnnData structure File format:- AnnData (.h5ad) Dimensions:- Cells (n_obs): 387,062- Genes (n_vars): 15,691 obs (cell metadata) columns:- dataset- time_numeric- celltype- time- day- dataset_label- donor- cell_type- title- species- n_genes- celltype_meta- celltype_rf var (gene metadata) columns:- n_cells Additional slots:- obsm: none- layers: none- uns: none

Keywords

Single-cell RNA-seq, Spatial Transcriptomics, Human Embryogenesis, Gene Language Model

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average