Jatyadi Taila is a classical Ayurvedic medicated oil extensively used in the management of wounds (Vrana), ulcers, burns, and inflammatory conditions. The pharmaceutical process of Sneha Kalpana plays a pivotal role in determining the quality, stability, and therapeutic efficacy of the formulation. The present study was undertaken to prepare Jatyadi Taila by three different pharmaceutical methods and to evaluate them through pharmaceutical observations and analytical parameters. Comparative assessment was carried out based on organoleptic characters, physicochemical constants, and chromatographic profiles. The study highlights the influence of pharmaceutical methodology on the extraction efficiency, stability, and standardisation of Jatyadi Taila.