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Report . 2023
License: CC BY NC SA
Data sources: Datacite
ZENODO
Report . 2023
License: CC BY NC SA
Data sources: Datacite
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A Bayesian Inference Based Computational Tool for Parametric and Nonparametric Medical Diagnosis

Technical Report XXV
Authors: Chatzimichail, Theodora; Hatjimihail, Aristides;

A Bayesian Inference Based Computational Tool for Parametric and Nonparametric Medical Diagnosis

Abstract

Medical diagnosis is the basis for treatment and management decisions in healthcare. Conventional methods for medical diagnosis commonly use established clinical criteria and fixed numerical thresholds. Such an approach is limited and may fail to capture the intricate relations between diagnostic tests and the varying prevalence of diseases. To explore this further, we have developed a freely available specialized computational tool that employs Bayesian inference to calculate the posterior probability of disease diagnosis. This novel software comprises three distinct modules, each designed to define and compare parametric and nonparametric distributions effectively. The tool analyzes datasets generated from two separate diagnostic tests performed on diseased and nondiseased populations. We demonstrate the utility of this software by analyzing fasting plasma glucose and glycated hemoglobin A1c data from the National Health and Nutrition Examination Survey (NHANES). Our results are validated using the oral glucose tolerance test as a reference standard, and we explore both parametric and nonparametric distribution models for the Bayesian diagnosis of diabetes mellitus.

Keywords

Diagnosis, Bayes Theorem

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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