ABSTRACT: Entrepreneurial operations are moving towards cloud-native software engineering solutions to scale, agility, and competitive advantage in any dynamic digital market. But startups and digital businesses are commonly subject to a gap in capability between moving these practices into practice and achieving quantifiable scalability of the business. Within this paper, a conceptual framework is developed based on the capability to combine multidimensional cloud-native software engineering practices, such as microservices architecture, containerization, serverless computing, DevOps automation, and API-first development, with the dynamic processes that make up the entrepreneurial business scaling. Using dynamic capability theory, digital agility views, and literature on socio-technical systems, the framework places emphasis on organizational capabilities that mediate the relations between technological adoption and scalability results and feedback loops that enhance continuous learning and adaptation. The paper also expands the framework to include the specific adoption pathways related to the stakeholders, especially start-up founders, CTOs, managers, incubators, accelerators, and investors, in enabling the successful adoption of cloud-native practices. The conceptual validation is done by using a systematic analytical reasoning process, which can be related to the correspondence of the framework components with theoretical propositions and expert judgment. The structure defines major system-level results, such as fast feature release, operational scalability, dynamic resource allocation, and cost-effective expansion, which are combined to increase the ability to scale of the entrepreneurial enterprises. This theoretical paper has its own impact on literature as it presents a multidimensional, socio-technical approach to cloud-native software engineering and business scalability, and mitigates the gap between technology adoption and strategic performance in start-ups. It provides practical information to practitioners and policymakers to develop agile, scalable, and resilient entrepreneurial ecosystems. It is proposed that further studies can empirically test the framework with respect to various industry settings, examine how the framework applies to platform-based and digital business, and the impact of the changing cloud technology on organizational capabilities. KEYWORDS: Cloud-Native Software Engineering, Entrepreneurial Business Scalability, Microservices, DevOps, API-First Development, Dynamic Capability, Digital Agility, Start-up Growth.