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Article . 2026
License: CC BY
Data sources: Datacite
ZENODO
Article . 2026
License: CC BY
Data sources: Datacite
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EARLY DETECTION OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION AS A PREDICTOR OF HEART FAILURE WITH PRESERVED EJECTION FRACTION

Authors: To'ychiyev, Hakim;

EARLY DETECTION OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION AS A PREDICTOR OF HEART FAILURE WITH PRESERVED EJECTION FRACTION

Abstract

Heart failure with preserved ejection fraction (HFpEF) has emerged as one of the most challenging and rapidly increasing cardiovascular syndromes worldwide. Despite normal or near-normal left ventricular ejection fraction, patients experience significant morbidity, reduced quality of life, and high mortality rates comparable to heart failure with reduced ejection fraction. Recent clinical evidence suggests that left ventricular diastolic dysfunction (LVDD) represents a pivotal pathophysiological substrate in the development of HFpEF. The early identification of diastolic abnormalities, therefore, plays a crucial role in preventing disease progression and improving long-term outcomes. This article reviews contemporary diagnostic approaches to early LV diastolic dysfunction, including echocardiographic markers, myocardial deformation imaging, and biomarker assessment. Particular emphasis is placed on the integration of Doppler echocardiography, tissue Doppler imaging, and speckle-tracking techniques in routine clinical practice. The clinical implications of early detection, therapeutic decision-making, and risk stratification are discussed. The findings underscore the importance of proactive screening strategies in high-risk populations to mitigate the global burden of HFpEF.

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Keywords

echocardiography, diastolic dysfunction, HFpEF

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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