The growing interest in environmentally friendly and sustainable agricultural practices has increased the relevance of biopreparations derived from microorganisms in plant cultivation. This article analyzes the effectiveness of microbial-based biopreparations in the cultivation of ornamental plants within the framework of school biology lessons. The study aims to evaluate not only the biological impact of these biopreparations on plant growth, development, and resistance to diseases, but also their pedagogical value in enhancing students’ practical skills and ecological awareness. The research is based on experimental observations conducted during biology classes, where ornamental plants were cultivated using selected microbial biopreparations, including biofertilizers and biostimulants, and compared with traditionally cultivated plants. Quantitative and qualitative indicators such as germination rate, growth dynamics, leaf coloration, flowering intensity, and overall plant vitality were systematically analyzed. The results demonstrate that the use of microorganism-derived biopreparations significantly improves plant growth parameters and stress tolerance, while reducing the need for chemical fertilizers. Moreover, integrating this topic into school biology lessons promotes students’ understanding of microbiological processes, sustainable agriculture, and the role of beneficial microorganisms in ecosystems. The study concludes that microbial biopreparations are not only effective tools for ornamental plant cultivation but also valuable educational resources for developing scientific thinking, environmental responsibility, and practical competence among school students.