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Preprint . 2026
License: CC BY
Data sources: Datacite
ZENODO
Preprint . 2026
License: CC BY
Data sources: Datacite
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Multifractal Temporal Complexity in Autism: Site-Robust Complementary Signal in the ABIDE Cohort

Authors: Dudas, David R.;

Multifractal Temporal Complexity in Autism: Site-Robust Complementary Signal in the ABIDE Cohort

Abstract

Reproducible analysis pipeline for multifractal detrended fluctuation analysis (MF-DFA) of resting-state fMRI in the ABIDE cohort (N=871, 20 sites, 111 brain regions). Demonstrates that multifractal features are inherently robust to multi-site scanner effects and provide complementary temporal complexity information that improves Riemannian connectivity-based ASD classification from 66.8% to 68.2%. Identifies the superior temporal gyrus as the primary locus where fractal dynamics correlate with clinical severity (ADOS) and cognitive ability (IQ, p_FDR=0.034). Includes site-effects ablation, ComBat harmonization, ensemble fusion, and clinical correlation modules.

Keywords

site harmonization, ABIDE, resting-state, multifractal analysis, fMRI, MF-DFA, temporal complexity, biomarker, autism spectrum disorder, hurst exponent

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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