This article explores the functional-syntactic roles of verbs in English and Karakalpak through a comparative approach. Verbs are examined as the core elements of sentence structure, responsible for predication, argument relations, tense, aspect, and modality. The analysis shows that English verbs function mainly within an analytic system supported by fixed word order and auxiliary verbs, whereas Karakalpak verbs operate in an agglutinative system where grammatical meanings are largely expressed through suffixation. Despite these typological differences, verbs in both languages fulfill similar communicative and syntactic functions.