The purpose of this review on hollow microballoon with a special focus on the novel different technologies and technique which are used for the preparation of hollow microballoon. The hollow microballoon, as versatile carriers for controlled drug delivery, have garnered significant attention in pharmaceutical research because they facilitate drug release kinetics and increase therapeutic efficacy. For medications with site-specific absorption, microballoon-based drug delivery devices have proven to be more significant in regulating release rate. These low density microballoons buoyant remain in the stomach enhance the availability of drug with narrow absorption windows. The microballoon prepared using different techniques and technologies such as solvent evaporation, solvent diffusion, spray-drying and hot-melt method’s. The evaluation of prepared hollow microballoon using such method like particle size, bulk density, tapped density etc,.Top of Form