OneK1K B-cell dataset used for MR.RGM real-data analysis

This record contains the real-data resources used in the OneK1K-based analyses of the MR.RGM and MR.RGM+ methods. The upload includes one R data archive: donor_b_cell.rda This file contains derived and curated data objects for B-cell samples from the OneK1K project, including:- donor-level covariates (age, sex, genotype PCs),- genotype dosage matrices aligned to donor IDs,- gene-level RNA count matrices aggregated at the donor level, and- genomic annotations for variants and genes. The data have been preprocessed to enable direct use in the real-data analysis scripts provided in the associated code repository. The files in this record are provided to ensure full reproducibility of the OneK1K real-data analyses reported in the associated manuscript. Original OneK1K data were generated by the OneK1K Consortium. This record redistributes derived and reorganized data products for methodological reproducibility only.

Keywords

Bayesian methods, Genotype data, B-Cell, Gene Expression, OneK1K, Mendelian Randomization Analysis, Causal network inference

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