10.5281/zenodo.18487134 A fundamental formula is presented that allows expressing any physical, mathematical, or biological constant through three basic dimensionless ratios withaccuracy better than 1%. The formula successfully approximates more than 50 fundamental constants, including the fine-structure constant α, speed of light c, reduced Planck constant ℏ, gravitational constant G, and others with accuracy < 1%. New predictions are discovered: a crystal with lattice period 1.888 ˚A, resonant energy 0.333 eV,biologically active frequency 142.857 Hz, optimal temperature 296.3 K. Statistical significance is confirmed on SPARC data (p < 0.0001). The formulaestablishes a fundamental law of nature: all physical systems are characterized by three quantum numbers (a, b, c) determining their harmonic, structural, and cyclicproperties. Keywords: fundamental constants, universal formula, quantum numbers, harmony, structure, cyclicity, predictive theory, particle physics, cosmology, crystallography.