Forensic Abstract: This paper challenges the ICD-11 classification of Burnout as a psychological phenomenon resulting from unsuccessful stress management. Through a neurobiological forensic audit, we reclassify the phenomenon as "Systemic Necrosis"—a physiological actuation of a "Hardware Lockout" response. We present evidence from Conserved Transcriptional Response to Adversity (CTRA) profiles and neuroimaging of moral injury to demonstrate that the human organism actively rejects "Semantic Void" environments. The study concludes that phenomena such as "Quiet Quitting" are evolutionary energy-conservation protocols (Ontological Strike) triggered by Thermodynamic Insolvency, requiring a fundamental shift from resilience training to the restoration of Neuro-Ontological Sovereignty. Forensic Biological Alert: Clinical audits confirm that subjects forcing productivity within a "Semantic Void" activate the CTRA Gene Profile, inducing a downregulation of antiviral defenses and a massive upregulation of proinflammatory cytokines. The organism literally inflames itself to physically prevent participation in the compromised system. This confirms that the pathology is not individual, but environmental—driven by Pathogenic Urbanicity and the "Flawed Man Protocol".