
En el presente trabajo de investigación, se estudió el efecto sobre el crecimiento capilar de extractos derivados de la planta del romero (Rosmarinus officinalis) de manera individual (aceite esencial, hidrolato y extracto alcohólico) y en conjunto (en forma de un champú y tónico capilar) en ratones macho de la línea C57BL6//BIOU, repartidos en 7 grupos distintitos: agua destilada (AD), aceite esencial (AE), extracto (ER), hidrolato (HR) y minoxidil al 5% (MXD). El crecimiento fue evaluado durante 5 semanas, mediante dos métodos: una escala de crecimiento con registro fotográfico y la medición de pelos tomados por tracción. El crecimiento capilar producido por estos tratamientos fue contrastado con un grupo control negativo (agua destilada) y control positivo (minoxidil al 5%). La escala de crecimiento empleada demostró que los ratones de los grupos AE, ER y HR; exhibían un crecimiento capilar considerable, sin embargo, esta escala demostró tener serias limitaciones a la hora de evaluar ratones con nevo melanocítico. Por su parte, la medición de longitud de los pelos, demostró que dichos grupos AE, ER y HR; presentan un crecimiento estadísticamente superior que el de los grupos control (p-valor < 0,05). Finalmente, se concluyó que los extractos empleados en esta investigación (aceite esencial, hidro
In the present research work, the effect on hair growth of extracts derived from the rosemary plant (Rosmarinus officinalis) individually (essential oil, hydrolate and alcoholic extract) and together (in the form of a shampoo and hair tonic) was studied in male mice of the C57BL6//BIOU line, divided into 5 different groups: distilled water (AD), essential oil (AE), extract (ER), hydrolate (HR) and minoxidil 5% (MXD). Growth was evaluated for 5 weeks, using two methods: a growth scale with photographic record and the measurement of hairs taken by traction. The hair growth produced by these treatments was contrasted with a negative control group (distilled water) and positive control (minoxidil 5%). The growth scale used showed that the mice of the AE, ER and HR groups exhibited considerable hair growth; however, this scale proved to have serious limitations when evaluating mice with melanocytic nevus. On the other hand, the measurement of hair length showed that the AE, ER and HR groups presented a statistically superior growth than the control groups (p-value < 0.05). Finally, it was concluded that the extracts used in this research (essential oil, hydrolate and alcoholic extract) stimulate hair growth to a greater extent than the commercial drug minoxidil.
hair growth, Rosmarinus officinalis, alopecia, extract, C57BL/6 mice
hair growth, Rosmarinus officinalis, alopecia, extract, C57BL/6 mice
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