According to the World Health Organisation (WHO, 2015), palliative care (PC) should be initiated early in the course of any chronic condition with a poor prognosis, in parallel with treatments aimed at prolonging survival, with the aim of improving the quality of life of patients and their families. PC plays a key role in ensuring dignity for people with incurable diseases, as recognised at national level by the National Recovery and Resilience Plan (PNRR) and Ministerial Decree No. 77/2022, which highlight its strategic function in the reorganisation of local care. However, the response to end-of-life needs is often fragmented, delayed and characterised by a predominantly medical-hospital approach, factors that make it difficult to ensure early and comprehensive care.As part of the PNRR, the Tuscany Health Ecosystem (THE) promotes Health Community Labs (HCLs): co-creation initiatives developed in collaboration with local stakeholders in the Tuscany region.The aim of this HCL is to understand whether the early and comprehensive approach to PC, implemented through support pathways for caregivers and operators, sharing spaces and initiatives aimed at well-being, can evolve from a local initiative to a scalable territorial model. To this end, the report illustrates the HCL's experience in PC services, with a focus on the Casa del Grano (CdG) project.Promoted by the Tutto è Vita Foundation in Cantagallo (PO), the CdG project, a co-housing facility for people with serious illnesses, proposes an innovative model of early care centred on mind, body, relationships, nature and spirituality, with the aim of fostering a sense of community and mutual support.In this context, HCL has launched a participatory process involving healthcare professionals, volunteers and institutions, with the aim of co-creating guidelines aimed at innovating the care of patients in PC, so as to improve the services offered by the CdG project and, at the same time, promote its more effective integration and dissemination within the Regional Health System (SSR) and replicability in other territorial contexts.The HCL covered in this report identified the CdG as its pilot model, from which the key elements of scalability were identified — such as integrated care pathways, clear communication, continuous training of operators and sustainability — which guided the definition of the guidelines.