This paper proposes a novel interpretive framework for the sacred geography of ancient Egypt, suggesting that the spatial arrangement of major temple districts and necropolis along the Nile Valley may reflect symbolic astronomical and hydrological motifs. Drawing on established Egyptian cosmological concepts—such as the Duat (underworld), circumpolar "imperishable" stars, and the life-giving role of the Nile inundation—the study explores potential parallels between the river's course and celestial patterns, including stellar alignments associated with renewal and the afterlife journey. The Theban region (Luxor–Karnak) is interpreted as evoking themes of rebirth and celestial stability, Middle Egypt temple complexes as transitional zones, and the Memphite necropolis (including Saqqara and Giza) as gateways to the underworld. This hypothetical model positions the Nile Valley as a terrestrial reflection of ideological cycles of descent, transformation, and ascent, integrating site orientations, textual references to stellar deities (e.g., Sopdet/Sirius), and hydrological symbolism. While remaining speculative, the framework aims to contribute to discussions of symbolic landscape organization in pharaonic Egypt, highlighting the interplay between geography, astronomy, and cosmology in temple planning and funerary ideology.