This repository contains all the simulation data produced in our study of the human erythrocyte plasma membrane. The simulation data includes both coarse-grained and all-atom resolution simulations, stored in the following repositories owing to large file sizes: Coarse-grained simulations (all files in the current repository): cg_analysis.zip: Analysis scripts, data, and graphs cg_setup.zip: Setup scripts, MDP files, topology and parameter files iter0.zip, iter1.zip, iter2.zip: Simulation iterations to equilibrate the membrane cholesterol asymmetry and packing area D-erythro sphingoid motif variant: Part 1: https://doi.org/10.5281/zenodo.18410613 Part 2: https://doi.org/10.5281/zenodo.18470516 3-keto sphingoid motif variant: Part 1: https://doi.org/10.5281/zenodo.18479188 Part 2: https://doi.org/10.5281/zenodo.18479447 Phyto sphingoid motif variant: Part 1: https://doi.org/10.5281/zenodo.18482504 Part 2: https://doi.org/10.5281/zenodo.18482789 Part 3: https://doi.org/10.5281/zenodo.18483613 Dihydro sphingoid motif variant: Part 1: https://doi.org/10.5281/zenodo.18480357 Part 2: https://doi.org/10.5281/zenodo.18481480 Simulation repositories also include analysis scripts and graphs used to produce Figures 2, 4, 5, 6, 7, 8, 9, 10, and 11 of the corresponding article (DOI pending).