Responsible tourism is a development trend in the tourism industry aimed at maximizing positive aspects and minimizing negative impacts from tourism. Besides achievements, tourism in Kien Giang Province also reveals many limitations that can be addressed through the approach of responsible tourism development. With the purpose of analyzing the current situation of responsible tourism development in Kien Giang Province based on content and territory according to tourists' perceptions, this study was conducted. Research data were collected via a survey with questionnaires administered to 400 tourists. Descriptive statistics and one-way ANOVA analysis methods were used to analyze the data. The research results reflect the highlights and limitations in the development of responsible tourism in Kien Giang regarding aspects such as product development, communication, labor usage, tourism management, community actions, operation of food service establishments, and accommodation facilities. Additionally, the differences in the development level of these aspects by surveyed locations were also clarified.