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ZENODO
Article . 2026
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2026
License: CC BY
Data sources: Datacite
ZENODO
Article . 2026
License: CC BY
Data sources: Datacite
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P-GLIKOPROTEINNING KO'KRAK SARATONI HUJAYRALARIDA DORILARGA QARSHILIKNI OSHIRISHDAGI AHAMIYATI

descriptionPublicationkeyboard_double_arrow_right Article 23 Jan 2026Publisher:Zenodo
Authors: Poyonov M.M.;

doi: 10.5281/zenodo.18353441 , 10.5281/zenodo.18353442

P-GLIKOPROTEINNING KO'KRAK SARATONI HUJAYRALARIDA DORILARGA QARSHILIKNI OSHIRISHDAGI AHAMIYATI

Abstract

P-glikoprotein (P-gp, ABCB1) ko‘krak saratoni hujayralarida kimyoterapiyaga chidamlilikni shakllantiruvchi asosiy ATP-bog‘liq efflyuks transporteri hisoblanadi. Ushbu maqolada P-gp ekspressiyasi, uning hujayra yashovchanligi va sitotoksiklikka ta’siri Western blotting, LDH va cell viability usullari asosida tahlil qilindi. Olingan natijalar P-gp yuqori ekspressiyasi dorilarining hujayra ichida to‘planishini kamaytirib, kimyoterapiya samaradorligini pasaytirishini ko‘rsatadi.

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green