
The biological process of wound healing is intricate and involves remodeling, proliferation, inflammation, and hemostasis. Herbal formulations are becoming more popular as safer substitutes for synthetic wound-healing agents due to their drawbacks. The goal of the current study was to create and assess a topical herbal gel with extracts of Punica granatum Linn peel and Tectona grandis Linn leaves for its potential to treat wounds. The presence of flavonoids, tannins, phenolic compounds, alkaloids, saponins, and steroids was confirmed by phytochemical screening after the extracts were made by cold maceration using 70% ethanol. Carbopol 934 was used as the gelling ingredient to create three gel formulations, which were then assessed for physicochemical characteristics and antibacterial efficacy. Superior antibacterial efficacy against Aspergillus niger and Escherichia coli was demonstrated by the mixed extract formulation.The results indicate that the formulated herbal gel is safe, stable, and effective for topical wound-healing applications.
Wound healing, Herbal gel, Tectona grandis Linn, Punica granatum Linn, Carbopol 934, Antimicrobial activity, Phytochemical screening, Topical drug delivery system
Wound healing, Herbal gel, Tectona grandis Linn, Punica granatum Linn, Carbopol 934, Antimicrobial activity, Phytochemical screening, Topical drug delivery system
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