This publication introduces the European Framework for Human Safety in High-Risk Digital & Technological Environments (EU-HSF) as a conceptual master framework designed to address emerging human safety risks across digital platforms, high-risk AI systems and future extreme operational environments. The framework proposes a unified, human-centred architecture integrating child protection in digital environments, AI responsibility and human oversight, psychological and neuro-safety, and human readiness for extreme and space-analog contexts. EU-HSF is presented as an early-stage, non-operational conceptual framework intended to support institutional reflection, expert dialogue and long-term governance development. It does not constitute a policy proposal, funding request or implementation plan. The framework is designed to be adaptable across regulatory, legislative and institutional contexts, with relevance to ongoing European and international discussions on preventive, human-centred governance in high-risk digital and technological domains.