This study investigates the multimodal features of discursive interaction in English and Uzbek, focusing on the integration of linguistic, visual, and pragmatic elements. By applying a comparative framework, this research examines how cultural and linguistic contexts influence communication strategies in both languages. Data were collected from public health campaigns, social media interactions, and everyday conversational exchanges. Findings reveal significant differences in the use of gestures, visual framing, and pragmatic markers, highlighting the role of culture in shaping multimodal discourse. The study contributes to cross-cultural communication research and offers practical implications for designing culturally sensitive messaging in digital media and public outreach campaigns.