The COVID-19 pandemic came with major challenges to the capacity of health systems to continue the delivery of essential health services including reproductive health care while, at the same time, tackling the pandemic. The purpose of this study is to assess the effects of the COVID-19 pandemic on access and utilization sexual and reproductive health services in some health units in Cameroon’s capital city, Yaoundé. This was done by comparing the consultations for reproductive health care recorded in selected health units in Yaoundé one year before the onset of the COVID-19 pandemic and those recorded during the pandemic year (2021). Interviews of reproductive service providers were conducted to find out the new difficulties faced as well as the solutions provided. Using data extracted from out-patient departments in these health units, this study found a significant reduction in the number of users seeking reproductive health services after March 2020, due to the COVID-19 pandemic scare and restrictions in all health units selected. Users mentioned fears of infection, and a fall in the quality of these services. Access was limited by demand and supply barriers including transportation disruptions, financial hardships, limited resources and legal restrictions. Faced with this situation, some health personnel developed tele-consultation techniques using telephones and some internet-based platforms, albeit with limited success. These findings call for the strengthening of health care systems for pandemic preparedness in Cameroon and elsewhere. This will enhance access to essential sexual and reproductive health care services in times of health emergencies.