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ZENODO
Book . 2026
License: CC BY
Data sources: ZENODO
ZENODO
Book . 2026
License: CC BY
Data sources: Datacite
ZENODO
Book . 2026
License: CC BY
Data sources: Datacite
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Metabolic Architecture: An Evidence-Based Approach to Lifestyle Medicine

descriptionPublicationkeyboard_double_arrow_right Book 20 Jan 2026Publisher:Zenodo
Authors: Karami, Mourad;

doi: 10.5281/zenodo.18308133 , 10.5281/zenodo.18308134

Metabolic Architecture: An Evidence-Based Approach to Lifestyle Medicine

Abstract

Metabolic Architecture is a systems-biology review synthesizing current evidence in nutritional biochemistry, circadian biology, exercise endocrinology, and neuroendocrinology. Moving beyond the caloric balance model, this work examines insulin signaling, mitochondrial bioenergetics, circadian entrainment, myokine-mediated endocrine communication, and HPA-axis regulation. Designed for medical students, clinicians, and health researchers, this text bridges molecular mechanisms with lifestyle-based clinical strategy.

Keywords

Metabolic Syndrome, Circadian Rhythms, Allostatic Load, HPA Axis, Myokines, Insulin Resistance, Glymphatic System, Mitochondrial Function

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    popularity
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    influence
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green