This study was conducted to examine the socio-economic-cultural factors that are affecting the mastery of science competencies of Grade V pupils. It utilized the descriptive-evaluative and qualitative method. Results of the study revealed that most of the respondents were high school graduates with a monthly income of 4,000 and below. Based on these findings, educational attainment and parents’ income have a significant relationship to pupil’s performance. Respondents were likewise aware that income, child-rearing practices and attitudes towards education greatly affect the competencies of pupils in Science & Health V.