Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ ZENODOarrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Other literature type . 2026
License: CC BY
Data sources: ZENODO
ZENODO
Other literature type . 2026
License: CC BY
Data sources: Datacite
ZENODO
Other literature type . 2026
License: CC BY
Data sources: Datacite
versions View all 2 versions
addClaim

Expression-Dependent Inversion of Gene Correlations and Diversity in Single Cells

Authors: De Jesus, Elias;

Expression-Dependent Inversion of Gene Correlations and Diversity in Single Cells

Abstract

This work presents a minimal structural framework for analyzing systems that exhibit sharp transitions, sensitivity concentration, and apparent universality across domains. By stripping the framework to its core assumptions, we show that many observed “corridor” effects—narrow regions where response, variance, or informational sensitivity peak—arise generically from bounded control parameters, smooth response functions, and finite resolution. The analysis clarifies which aspects of the framework are mathematically necessary consequences of scaling and encoding, and which aspects may carry empirical or heuristic value. Emphasis is placed on encoding dependence, resolution effects, and the distinction between intrinsic structure and projection-induced artifacts. Rather than proposing a new physical theory, this work functions as a diagnostic lens: a way to test whether observed coherence, universality, or criticality reflects genuine system structure or emerges from representation, measurement, or aggregation choices. The framework is intentionally domain-agnostic and may be applied to problems in physics, computation, information theory, and complex systems analysis.

Keywords

• finite-size effects • scaling and resolution • encoding dependence • sensitivity concentration • critical corridors • information geometry • representation invariance • projection artifacts • complexity diagnostics • universality testing • bounded response systems • structural vs observational effects, • finite-size effects • scaling and resolution • encoding dependence • sensitivity concentration • critical corridors • information geometry • representation invariance • projection artifacts • complexity diagnostics • universality testing • bounded response systems • structural vs observational effects

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green