Abstract This study is a comparative analysis of the relative effectiveness of discussion and demonstration methods on secondary school students’ performance in chemistry in Ogbia, Bayelsa State. Quasi experimental research design was adopted for the study The population of the study comprised of1342 SS2 science student in all the 37 public secondary school in Ogbia Local Government Area of Bayelsa State and a sample size of 100 study was purposively drawn from the population of chemistry student in the study area. The Chemistry Achievement Test (CAT) used for collection of data and data collected were analyzed using mean and standard deviation while the hypotheses was tested using independence t-test at 0.05 level of significance. Finding revealed that, student taught using demonstration methods perform better than those taught using discussion. It also showed that female students taught using demonstration method perform better than their male counterparts It was recommended among others that teachers should incorporate more demonstration-based techniques in their Chemistry lessons to facilitate better understanding and retention of the material.