An experiment entitled “Response of organic manures and varieties on growth and yield of cowpea at Bharatpur, Chitwan” was conducted in Agronomy farm of Nepal Polytechnic Institute during spring season 2022. The experiment was conducted in two factorial Randomized Complete Block Design with three replications and ten treatments. The treatments were set as two variety: V1: Surya and V2: Prakash as factor A and 20 kg N from different sources of organic manures (OM): OM1: FYM (0.5%N) 4 t ha-1, OM2: Poultry manure (5%N) 0.4t ha-1, OM3: Vermicompost (2.5% N) 0.8 t ha-1, OM4: Suchit biofertilizer (8.72% N) 0.23 t ha-1, OM5: Mustard oil cake (5.2% N) 0.39 t ha-1 as factor B. The main objective of the experiment was to find out the best variety and good organic manure for getting better yield of cowpea under rainfed condition. Results revealed that the variety Surya produced the highest grain yield (1.01 t ha-1) followed by Prakash (0.91 t ha-1). In case of organic manures, the highest grain yield (1.37 t ha-1) was obtained in 4 t ha-1 of FYM applied plot. The interaction effect between variety and organic manures showed that the variety Surya along with 4 t ha-1 FYM showed maximum grain yield (1.41 t ha-1). From this experiment, it is concluded that the use of variety Surya with 4 tons of FYM ha-1 gives the highest productivity with better economic return compared to all other treatments.