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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao ZENODOarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
ZENODO
Dataset . 2026
License: CC BY
Data sources: ZENODO
ZENODO
Dataset . 2026
License: CC BY
Data sources: Datacite
ZENODO
Dataset . 2026
License: CC BY
Data sources: Datacite
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Sanger sequencing files of SCNN1A exon 2-3-4 of Afro-Colombian patients with apparent resistant hypertension

Authors: Gutierrez Medina, Juan David;

Sanger sequencing files of SCNN1A exon 2-3-4 of Afro-Colombian patients with apparent resistant hypertension

Abstract

We studied the prevalence of genetic variants in the ENaC genes and their association with renin-aldosterone profiles in Afro-Colombian patients with apparent resistant hypertension. From our study population we selected 7 random samples for the Nanopore sequencing of most of the coding region of the SCNN1A gene. As all the participants were from the same Colombian town of Puerto Tejada, we wanted to rule out the possibility of genetic variants common to this specific population. However, amplifying through conventional PCR the exon 2-3-4 SCNN1A region in one amplicon was difficult as the PCR product was full of unspecific amplicons. To solve this problem, we decided to perform sanger sequencing individually in these exons in those 7 samples. These are the ab1 files of the electropherograms.

Keywords

Genetic Variation/genetics, Hypertension, Epithelial Sodium Channels

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average