In the highly competitive retail sector, effective customer relationship management (CRM) has become a strategic necessity for achieving sustainable business growth. CRM practices enable retail enterprises to build long-term customer relationships, enhance satisfaction, and improve customer retention. This study examines the impact of CRM practices on business growth in Indian retail enterprises. Primary data were collected from 195 retail employees and managers through a structured questionnaire. The study analyzes the influence of customer data management, service personalization, complaint handling systems, and loyalty programs on sales growth, customer retention, and brand loyalty. The findings reveal a significant positive relationship between CRM practices and business growth, emphasizing the importance of customer-centric strategies in improving retail competitiveness and profitability.