Lifestyle disorders—including hypertension, diabetes, obesity, dyslipidemia and stress-related illnesses—are increasing at an alarming rate globally. Non-pharmacological interventions such as meditation have arose as effective complements to conventional healthcare. This quantitative study examines the impact of Rajyoga Meditation on selected physiological and psychological parameters associated with lifestyle disorders. A sample of 60 adults (aged 30–65) with diagnosed lifestyle disorders was selected using purposive sampling. Participants practiced Rajyoga Meditation for 30 minutes daily over 8 weeks. Pre and post-intervention scores for blood pressure, fasting blood sugar, lipid profile, BMI and Perceived Stress Scale (PSS) were analyzed using descriptive statistics and paired t-tests. The results demonstrated statistically significant improvements (p < 0.05) in systolic and diastolic blood pressure, fasting glucose, triglycerides, BMI and perceived stress levels following the meditation intervention. The study concludes that Rajyoga Meditation is a safe, effective and low-cost non-pharmacological modality for managing and preventing lifestyle disorders. It has strong potential for integration into community health programs and hospital-based lifestyle interventions.