Catastrophic drug abuse is prevailing all over the world and its incidence and prevalence rate is higher in developing countries. Drug menace is a big problem in today’s world and it effects morally and spiritually both family and community. Due to chronic stress workload, emotional exhaustion emergency duties of handling both acute and drug abusers, lack of institutional support, electronic record maintaining fatigue, personal medico stress of family, anxiety, depression, family conflict and sometimes suicidal ideas. Sometimes burnout and job stress among medical professionals are significant risk factors for substance misuse and pushes suicidal rate of medicos. Though WHO, AMA and Indian medical association have raised and are raising concerns about mental health crises in healthcare workers and it becomes pivotal to government to come up with a comprehensive approach such as institutional programs like physician health programs (PHPs), cognitive behavioral therapy (CBT), mindfulness, supervised rehabilitation and peer support networks to save the endanger medical fraternity of healthcare’s dealing with drug abusers. Objectives: 1) To aware people about drug addiction and its consequences 2) To analyze burnouts in medical profession. Methods: Various drug abuse centers were visited randomly and interview method was used to collect data from medical professionals like doctors, nurses, data entry employees. The study has concluded that drug abuse patients create a burden on medical professionals due to the complex physical, psychological and social issues they present. Medical professionals face emotional stress, time constraints and ethical challenges while dealing with such patients. Effective management demands compassion, patience and specialized training to already overburdened medical systems.