In this paper we discuss, under a critical point of view, the current Information Science landscape and some future prospects regarding contemporary information phenomena. We present thoughts about the process of thematic deflation of Information Science, through the analysis of the research objects currently under development in this field. In addition to this, we look at the process of absorption of these and other relevant objects in distinguished knowledge fields. We seek to challenge the emphasis and the volume of interdisciplinary research within the field, and present some comments about what might be the results of such processes for the future of Information Science. Subsequently, we analyze the impact in the Information Science field due to phenomena like information boom, the consolidation of the social networks as interactive spaces, cloud computing, as well as other key elements.